Depersonalization Forum

Please use this forum to discuss information directly related to Depersonalization Disorder. We welcome you to share your own personal experiences with others as well as any treatment or study programs you may know about. We have been forced to restructure the Forum so we could have editing access as needed and be able to Archive older comments once they disappear.  Sorry for the temporary inconvenience, but now we will able to post older material for reference.

Depersonalization Forum
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Re: Naloxone to improve DPD?

Hey

I have been suffering from DPD for a little over a year now and i have also read of the studies done with the drug Naloxone. I have tried many prescription drugs and none have helped so i have just accepted my DP and am living my life in a constant struggle with it every day. It would be amazing if this drug actually worked in combatting DP, and even putting it into complete remission as i read in the cases of three individuals who suffered from it. I was just wondering if you have found anything else out about Naloxone and its effectivness over DP. my email is david038289@gmail.com id really appreciate any feedback from you thanks!

Re: Naloxone to improve DPD?

The Russian study used naloxone, while the follow up study in 2005 by Simeon and Knutelska used naltrexone. While the latter is twice as potent as naloxone, it is not as effective in "hitting its target area" so to speak. Overall the naloxone study looks very promising and further investigation is warranted.